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A Multi-arm, Open-label, Phase 1 Trial to Evaluate the Safety and Tolerability, Pharmacokinetics and Anti-tumour Activity of MST-0312 When Given Alone and in Combination With Anticancer Treatments in Subjects With Solid Malignancies

Trial Profile

A Multi-arm, Open-label, Phase 1 Trial to Evaluate the Safety and Tolerability, Pharmacokinetics and Anti-tumour Activity of MST-0312 When Given Alone and in Combination With Anticancer Treatments in Subjects With Solid Malignancies

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 10 Jun 2026

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At a glance

  • Drugs MST 0312 (Primary) ; Pembrolizumab (Primary)
  • Indications Bladder cancer; Colorectal cancer; Gastrointestinal cancer; Multiple myeloma; Non-small cell lung cancer; Skin cancer; Solid tumours; Triple negative breast cancer
  • Focus Adverse reactions; First in man
  • Acronyms MST-0312-1001; STARLYS
  • Sponsors Mestag Therapeutics

Most Recent Events

  • 28 May 2026 Planned number of patients changed from 42 to 157.
  • 28 May 2026 Status changed from not yet recruiting to recruiting.
  • 28 May 2026 Planned End Date changed from 31 Dec 2026 to 31 Dec 2029.

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