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A Phase 1b Open-label Study to Evaluate the Safety and Tolerability of MEDI4736 in Combination with Tremelimumab in Subjects with Advanced Non-Small Cell Lung Cancer

Trial Profile

A Phase 1b Open-label Study to Evaluate the Safety and Tolerability of MEDI4736 in Combination with Tremelimumab in Subjects with Advanced Non-Small Cell Lung Cancer

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 10 May 2023

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At a glance

  • Drugs Durvalumab (Primary) ; Tremelimumab (Primary)
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors AstraZeneca; MedImmune

Most Recent Events

  • 03 May 2023 Results of phase 1b assessing (n=78; between October 25, 2013, and September 17, 2019) the safety and efficacy of durvalumab plus tremelimumab in adults with Advanced non-small cell lung cancer, published in the Journal of Thoracic Oncology.
  • 29 Oct 2019 Status changed from active, no longer recruiting to completed.
  • 30 Jul 2019 Planned End Date changed from 24 Apr 2019 to 17 Sep 2019.

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