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A Phase 2, Open-label, Multicenter Study to Evaluate the Safety and Clinical Activity of Durvalumab in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisone (R-CHOP) or With Lenalidomide Plus R-CHOP (R2-CHOP) in Subjects With Previously Untreated, High-Risk Diffuse Large B-Cell Lymphoma

Trial Profile

A Phase 2, Open-label, Multicenter Study to Evaluate the Safety and Clinical Activity of Durvalumab in Combination With Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisone (R-CHOP) or With Lenalidomide Plus R-CHOP (R2-CHOP) in Subjects With Previously Untreated, High-Risk Diffuse Large B-Cell Lymphoma

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Sep 2023

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At a glance

  • Drugs Durvalumab (Primary) ; Lenalidomide (Primary) ; Cyclophosphamide; Doxorubicin; Prednisolone; Prednisolone; Prednisone; Prednisone; Rituximab; Vincristine
  • Indications Diffuse large B cell lymphoma
  • Focus Therapeutic Use
  • Sponsors Celgene Corporation; Celgene International SARL

Most Recent Events

  • 19 Aug 2022 Status changed from active, no longer recruiting to completed.
  • 17 Jul 2022 This trial has been completed in Austria ,according to European Clinical Trials Database record.
  • 01 Feb 2022 Results published in the International Journal of Hematology

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