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Randomized Phase II Trial of Durvalumab (MEDI4736) and Tremelimumab Administered in Combination Versus Sequentially in Recurrent Platinum-Resistant Epithelial Ovarian Cancer

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Trial Profile

Randomized Phase II Trial of Durvalumab (MEDI4736) and Tremelimumab Administered in Combination Versus Sequentially in Recurrent Platinum-Resistant Epithelial Ovarian Cancer

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 10 Oct 2025

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At a glance

  • Drugs Durvalumab (Primary) ; Tremelimumab (Primary)
  • Indications Carcinoma; Fallopian tube cancer; Ovarian cancer; Peritoneal cancer
  • Focus Therapeutic Use

Most Recent Events

  • 19 Sep 2025 Status changed from active, no longer recruiting to completed.
  • 09 Jul 2025 According to LIXTE Biotechnology Holdings media release, New Clinical Findings from this trial Published in Scientific Journal Nature.
  • 10 Sep 2024 Planned End Date changed from 15 Dec 2024 to 30 Sep 2025.

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