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A Randomized Trial of Durvalumab (MEDI4736) and Tremelimumab ± Platinum-Based Chemotherapy in Patients With Metastatic (Stage IV) Squamous or Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

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Trial Profile

A Randomized Trial of Durvalumab (MEDI4736) and Tremelimumab ± Platinum-Based Chemotherapy in Patients With Metastatic (Stage IV) Squamous or Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 01 Oct 2025

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At a glance

  • Drugs Durvalumab (Primary) ; Tremelimumab (Primary) ; Carboplatin; Cisplatin; Gemcitabine; Pemetrexed
  • Indications Non-small cell lung cancer; Squamous cell cancer
  • Focus Proof of concept; Therapeutic Use

Most Recent Events

  • 29 Aug 2025 Planned End Date changed from 30 Jun 2025 to 30 Dec 2025.
  • 22 Apr 2025 Planned End Date changed from 31 Dec 2024 to 30 Jun 2025.
  • 09 Feb 2024 Planned End Date changed from 31 Dec 2023 to 31 Dec 2024.

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