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An Open-Label Phase 2 Trial of Acalabrutinib Plus Obinutuzumab in Patients With Untreated, Low Tumor Burden Follicular Lymphoma and Other Indolent Non-Hodgkin Lymphomas

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Trial Profile

An Open-Label Phase 2 Trial of Acalabrutinib Plus Obinutuzumab in Patients With Untreated, Low Tumor Burden Follicular Lymphoma and Other Indolent Non-Hodgkin Lymphomas

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 12 Feb 2026

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At a glance

  • Drugs Acalabrutinib (Primary) ; Obinutuzumab (Primary)
  • Indications Follicular lymphoma; Lymphoproliferative disorders; Mantle-cell lymphoma; Marginal zone B-cell lymphoma; Non-Hodgkin's lymphoma; Waldenstrom's macroglobulinaemia
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 09 Feb 2026 Planned End Date changed from 15 Jan 2026 to 15 Jan 2027.
  • 09 Feb 2026 Planned primary completion date changed from 23 Sep 2025 to 23 Sep 2026.
  • 27 Mar 2025 Planned primary completion date changed from 15 Jan 2025 to 23 Sep 2025.

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